US River Cruises

American Cruise Lines offers personalized, small ship river cruises throughout the United States. Cruise the Mississippi River, Columbia and Snake Rivers, the Northeast United States, Southeast United States, Puget Sound, and Alaska. American Cruise Lines is Small Ship Cruising Done Perfectly. Discover more online or request a free brochure.

Featured Cruises

Mississippi River Cruises

Cruise the Mississippi River aboard the new American Eagle or Queen of the Mississippi.  Experience the fascinating history, culture and cuisine of the American heartland from the waters of Mighty Mississippi, Cumberland and Ohio Rivers. American Eagle cruises begin April 2015. Cruise from New Orleans, Memphis, Nashville, or St Paul with ten Mississippi River cruise itineraries. Learn more

Columbia and Snake River Cruises

Navigate the legendary route pioneered by Lewis and Clark as we cruise the Columbia and Snake Rivers aboard Queen of the West. Admire the natural splendor of the Columbia River Gorge and Mount St. Helens. Enjoy guided tours of historic Fort Clatsop, and the iconic frontier town of Pendleton, OR. Learn More

Puget Sound and San Juan Islands Cruise

Cruising Puget Sound is an unforgettable adventure filled with natural beauty and wildlife, Join us aboard American Spirit as we explore everything the region has to offer from the gardens of Victoria to whale watching on the sundeck. Learn More

Southeast United States Cruises

Explore the protected waterways of the Southeast United States with a memorable cruise along the East Coast Intracoastal waterway, Chesapeake Bay or the Great Rivers of Florida aboard our modern fleet of luxurious river boats. Captivating onboard experts and guided shore excursions illuminate local history and culture as we explore these iconic waterways. Learn more

New England Islands Cruise

Cruise the spectacular protected waterways of New England starting in May. Spend eight days exploring the island gems of Nantucket, Martha's Vineyard and Block Island in a single cruise. Discover the maritime history, friendly culture and renowned seafood of New England with American Cruise Lines. Learn More

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